{"id":25,"date":"2026-06-18T10:10:49","date_gmt":"2026-06-18T08:10:49","guid":{"rendered":"https:\/\/biologistjournal.com\/ko\/2026\/06\/18\/%eb%b9%84%eb%a7%8c%ec%9d%b4-%ec%9c%a0%ec%a0%84%ec%9e%90%ec%99%80-%ed%98%b8%eb%a5%b4%eb%aa%ac-%ec%82%ac%ec%9d%b4%ec%97%90%ec%84%9c-%eb%b9%84%eb%b0%80%ec%9d%84-%eb%93%9c%eb%9f%ac%eb%82%b4%eb%8b%a4\/"},"modified":"2026-06-18T10:11:37","modified_gmt":"2026-06-18T08:11:37","slug":"%eb%b9%84%eb%a7%8c%ec%9d%b4-%ec%9c%a0%ec%a0%84%ec%9e%90%ec%99%80-%ed%98%b8%eb%a5%b4%eb%aa%ac-%ec%82%ac%ec%9d%b4%ec%97%90%ec%84%9c-%eb%b9%84%eb%b0%80%ec%9d%84-%eb%93%9c%eb%9f%ac%eb%82%b4%eb%8b%a4","status":"publish","type":"post","link":"https:\/\/biologistjournal.com\/ko\/2026\/06\/18\/%eb%b9%84%eb%a7%8c%ec%9d%b4-%ec%9c%a0%ec%a0%84%ec%9e%90%ec%99%80-%ed%98%b8%eb%a5%b4%eb%aa%ac-%ec%82%ac%ec%9d%b4%ec%97%90%ec%84%9c-%eb%b9%84%eb%b0%80%ec%9d%84-%eb%93%9c%eb%9f%ac%eb%82%b4%eb%8b%a4\/","title":{"rendered":"\ube44\ub9cc\uc774 \uc720\uc804\uc790\uc640 \ud638\ub974\ubaac \uc0ac\uc774\uc5d0\uc11c \ube44\ubc00\uc744 \ub4dc\ub7ec\ub0b4\ub2e4"},"content":{"rendered":"

\"\ube44\ub9cc\uc774<\/p>\n

\ube44\ub9cc\uc774 \uc720\uc804\uc790\uc640 \ud638\ub974\ubaac \uc0ac\uc774\uc5d0\uc11c \ube44\ubc00\uc744 \ub4dc\ub7ec\ub0b4\ub2e4<\/h1>\n

\ube44\ub9cc\uc740 \ud604\uc7ac \uc804 \uc138\uacc4 \uc778\uad6c\uc758 \uc57d 30%\ub97c \ucc28\uc9c0\ud558\uba70, \uc774\ub294 1975\ub144 \uc774\ud6c4\ub85c 3\ubc30\ub098 \uc99d\uac00\ud55c \uc218\uce58\uc774\ub2e4. \uc624\ub7ab\ub3d9\uc548 \uc5d0\ub108\uc9c0 \uc12d\ucde8\uc640 \uc18c\ubaa8\uc758 \ub2e8\uc21c \ubd88\uade0\ud615\uc73c\ub85c \uc5ec\uaca8\uc84c\ub358 \uc774 \ubcf5\uc7a1\ud55c \uc9c8\ubcd1\uc740 \uc0ac\uc2e4 \uc720\uc804\uc790, \ud658\uacbd, \ud638\ub974\ubaac \uc2e0\ud638 \uac04\uc758 \ubc00\uc811\ud55c \uc0c1\ud638\uc791\uc6a9\uc758 \uacb0\uacfc\uc774\ub2e4. \uc774\ub97c \ub4b7\ubc1b\uce68\ud558\ub294 \uba54\ucee4\ub2c8\uc998\uc774 \uc810\ucc28 \ub354 \uc798 \uc774\ud574\ub418\uace0 \uc788\uc73c\uba70, \uc774\ub294 \ub354 \ud45c\uc801\ud654\ub418\uace0 \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc\ubc95\uc73c\ub85c \uc774\uc5b4\uc9c0\uace0 \uc788\ub2e4.<\/p>\n

\uc774\ub7ec\ud55c \ubc1c\uc804\uc758 \ud575\uc2ec\uc5d0\ub294 1994\ub144 \uc9c0\ubc29 \uc138\ud3ec\uc5d0\uc11c \uc0dd\uc131\ub418\ub294 \ud638\ub974\ubaac\uc778 \ub819\ud2f4\uc758 \ubc1c\uacac\uc774 \uc788\ub2e4. \ub819\ud2f4\uc758 \uc5ed\ud560\uc740 \ub2e8\uc21c\ud558\uc9c0\ub9cc \ub9e4\uc6b0 \uc911\uc694\ud558\ub2e4: \ub1cc\uc5d0\uac8c \uc5d0\ub108\uc9c0 \uc800\uc7a5 \uc218\uc900\uc744 \uc54c\ub824\uc8fc\uc5b4 \uc2dd\uc695\uacfc \uc5d0\ub108\uc9c0 \uc18c\ubaa8\ub97c \uc870\uc808\ud558\ub294 \uac83\uc774\ub2e4. \ube44\ub9cc\uc778 \uc0ac\ub78c\ub4e4\uc5d0\uc11c \ub819\ud2f4 \uc218\uce58\ub294 \uc885\uc885 \ub192\uc9c0\ub9cc, \ub1cc\ub294 \ub819\ud2f4 \uc2e0\ud638\uc5d0 \ub35c \ubbfc\uac10\ud574\uc9c0\ub294\ub370, \uc774\ub97c \ub819\ud2f4 \uc800\ud56d\uc131\uc774\ub77c\uace0 \ud55c\ub2e4. \uc774 \ud604\uc0c1\uc740 \ucd08\uae30\uc5d0 \uae30\ub300\ud588\ub358 \ubc14\uc640\ub294 \ub2ec\ub9ac \ub819\ud2f4\uc744 \uae30\ubc18\uc73c\ub85c \ud55c \uce58\ub8cc\uc758 \ud6a8\ub2a5\uc744 \ud06c\uac8c \uc81c\ud55c\ud55c\ub2e4.<\/p>\n

\ub3d9\uc2dc\uc5d0, \ub610 \ub2e4\ub978 \ud638\ub974\ubaac\uc778 \uae00\ub8e8\uce74\uace4 \uc720\uc0ac \ud3a9\ud0c0\uc774\ub4dc-1(GLP-1)\uc774 \uc720\ub9dd\ud55c \uce58\ub8cc \ub300\uc0c1\uc73c\ub85c \ubd80\uc0c1\ud558\uace0 \uc788\ub2e4. GLP-1\uc740 \uc2dd\uc0ac \ud6c4 \uc7a5\uc5d0\uc11c \ubd84\ube44\ub418\uba70, \uc5ec\ub7ec \uce21\uba74\uc5d0\uc11c \uc791\uc6a9\ud55c\ub2e4: \uc2dd\uc695\uc744 \uc904\uc774\uace0, \uc704 \ubc30\ucd9c\uc744 \ub2a6\ucd94\uba70, \uc778\uc290\ub9b0 \ubd84\ube44\ub97c \uc790\uadf9\ud558\uace0 \uc778\uc290\ub9b0 \ubbfc\uac10\uc131\uc744 \uac1c\uc120\ud55c\ub2e4. \ub819\ud2f4\uacfc \ub2ec\ub9ac, GLP-1 \uc218\uc6a9\uccb4\ub294 \ube44\ub9cc\uc778 \uc0ac\ub78c\ub4e4\uc5d0\uc11c\ub3c4 \uae30\ub2a5\uc131\uc744 \uc720\uc9c0\ud558\uae30 \ub54c\ubb38\uc5d0 \uce58\ub8cc \ud45c\uc801\uc73c\ub85c \uc801\ud569\ud558\ub2e4.<\/p>\n

GLP-1 \uc218\uc6a9\uccb4 \uc791\uc6a9\uc81c\uc778 \uc138\ub9c8\uae00\ub8e8\ud0c0\uc774\ub4dc\ub098 \ub9ac\ub77c\uae00\ub8e8\ud0c0\uc774\ub4dc\uc640 \uac19\uc740 \uce58\ub8cc\uc81c\ub294 \ube44\ub9cc \uad00\ub9ac\ub97c \ud601\uc2e0\uc801\uc73c\ub85c \ubc14\uafb8\uc5c8\ub2e4. \uc774\ub4e4\uc740 \uccb4\uc911 \uac10\ub7c9\uc744 \uc720\uc758\ubbf8\ud558\uac8c \uc720\ub3c4\ud558\uba70, \uc885\uc885 10% \uc774\uc0c1 \uac10\ub7c9\ud560 \uc218 \uc788\uc73c\uba70, \ud608\ub2f9 \uc870\uc808\uc744 \uac1c\uc120\ud558\uace0 \uc2ec\ud608\uad00\uacc4 \uc704\ud5d8\uc744 \uc904\uc778\ub2e4. \uc774\ub4e4\uc758 \uc791\uc6a9 \uba54\ucee4\ub2c8\uc998\uc740 GLP-1\uc758 \uc790\uc5f0\uc801 \ud6a8\uacfc\ub97c \uc7a5\uae30\uac04 \ubaa8\ubc29\ud558\ub294 \uac83\uc73c\ub85c, \ud654\ud559\uc801 \ubcc0\ud615\uc744 \ud1b5\ud574 \uc2e0\uccb4 \ub0b4 \ube60\ub978 \ubd84\ud574\ub97c \ubc29\uc9c0\ud55c\ub2e4.<\/p>\n

\uc720\uc804\ud559 \ub610\ud55c \ube44\ub9cc \uc18c\uc778\uc5d0\uc11c \ud575\uc2ec\uc801\uc778 \uc5ed\ud560\uc744 \ud55c\ub2e4. \ub819\ud2f4\uc774\ub098 \uadf8 \uc218\uc6a9\uccb4 \uc720\uc804\uc790\uc758 \ud76c\uadc0 \ub3cc\uc5f0\ubcc0\uc774\ub294 \uc5b4\ub9b0 \uc2dc\uc808\ubd80\ud130 \uc2ec\ud55c \ube44\ub9cc\uc744 \uc720\ubc1c\ud55c\ub2e4. \ub354 \ud754\ud558\uac8c\ub294 \uc218\ubc31 \uac1c\uc758 \uc720\uc804\uc790\uc5d0\uc11c \ubc1c\uacac\ub418\ub294 \uc0ac\uc18c\ud55c \uc720\uc804\uc801 \ubcc0\uc774\uac00 \ucd95\uc801\ub418\uc5b4 \uc704\ud5d8\uc744 \uc99d\uac00\uc2dc\ud0a8\ub2e4. \uadf8 \uc911\uc5d0\uc11c\ub3c4 FTO \uc720\uc804\uc790\ub294 \uccb4\uc9c8\ub7c9\uc9c0\uc218\uc5d0 \uac00\uc7a5 \ud070 \uc601\ud5a5\uc744 \ubbf8\uce58\ub294 \uc720\uc804\uc790 \uc911 \ud558\ub098\uc774\ub2e4. \uc774\ub7ec\ud55c \uc720\uc804\uc801 \uc18c\uc778\uc740 \ud658\uacbd\uacfc \uc0c1\ud638\uc791\uc6a9\ud55c\ub2e4: \ud48d\ubd80\ud55c \uc2dd\ub2e8\uacfc \uc88c\uc2dd \uc0dd\ud65c \ubc29\uc2dd\uc774 \uadf8 \uc601\ud5a5\uc744 \uc99d\ud3ed\uc2dc\ud0a8\ub2e4.<\/p>\n

DNA\uc758 \uc790\uc5f0\uc801 \ubcc0\uc774\uc778 \ub2e4\ud615\uc131 \ub610\ud55c \uce58\ub8cc\uc5d0 \ub300\ud55c \ubc18\uc751\uc5d0 \uc601\ud5a5\uc744 \ubbf8\uce5c\ub2e4. \uc608\ub97c \ub4e4\uc5b4, GLP-1 \uc218\uc6a9\uccb4 \uc720\uc804\uc790\uc758 \ud2b9\uc815 \ubcc0\uc774\ub294 \uc791\uc6a9\uc81c\uc758 \ud6a8\ub2a5\uc744 \ubcc0\ud654\uc2dc\ucf1c, \uc77c\ubd80 \ud658\uc790\uac00 \ub2e4\ub978 \ud658\uc790\ubcf4\ub2e4 \ub354 \uc798 \ubc18\uc751\ud558\ub294 \uc774\uc720\ub97c \uc124\uba85\ud55c\ub2e4. \uc774\ub7ec\ud55c \ubc1c\uacac\ub4e4\uc740 \ub9de\ucda4\ud615 \uc758\ud559\uc758 \uc911\uc694\uc131\uc744 \uac15\uc870\ud558\uba70, \uc720\uc804\uc801 \ud504\ub85c\ud30c\uc77c\uc774 \uac00\uc7a5 \uc801\ud569\ud55c \uce58\ub8cc\ubc95 \uc120\ud0dd\uc744 \uc548\ub0b4\ud560 \uc218 \uc788\uc74c\uc744 \uc2dc\uc0ac\ud55c\ub2e4.<\/p>\n

\ub819\ud2f4\uacfc GLP-1 \uac04\uc758 \uc0c1\ud638\uc791\uc6a9\uc740 \ub610 \ub2e4\ub978 \ud765\ubbf8\ub85c\uc6b4 \uc5f0\uad6c \uc8fc\uc81c\uc774\ub2e4. \uc5f0\uad6c\uc5d0 \ub530\ub974\uba74 GLP-1\uc774 \uc7a5\ub0b4 \ubbf8\uc0dd\ubb3c\uc744 \ud1b5\ud574 \ub819\ud2f4 \ubbfc\uac10\uc131\uc744 \ubd80\ubd84\uc801\uc73c\ub85c \ud68c\ubcf5\uc2dc\ud0ac \uc218 \uc788\uc74c\uc744 \ubcf4\uc5ec\uc900\ub2e4. \uc774\ub7ec\ud55c \uc2dc\ub108\uc9c0\ub294 \ub450 \ud638\ub974\ubaac\uc744 \uacb0\ud569\ud55c \ubcf5\ud569 \uc694\ubc95\uc744 \ud1b5\ud574 \ud6a8\uacfc\ub97c \uadf9\ub300\ud654\ud560 \uc218 \uc788\ub294 \uac00\ub2a5\uc131\uc744 \uc5f4\uc5b4\uc900\ub2e4. GLP-1\uacfc \ub610 \ub2e4\ub978 \uc7a5 \ud638\ub974\ubaac\uc778 GIP \uc218\uc6a9\uccb4\ub97c \ub3d9\uc2dc\uc5d0 \ud65c\uc131\ud654\ud558\ub294 \ud2f0\ub974\uc81c\ud30c\ud2f0\ub4dc\uc640 \uac19\uc740 \ubd84\uc790\ub294 \uc774\ubbf8 GLP-1\ub9cc \ud45c\uc801\ud654\ud558\ub294 \uce58\ub8cc\uc81c\ubcf4\ub2e4 \uc6b0\uc218\ud55c \ud6a8\ub2a5\uc744 \uc785\uc99d\ud588\ub2e4.<\/p>\n

\uadf8\ub7ec\ub098 \uc774\ub7ec\ud55c \uce58\ub8cc\uc801 \ubc1c\uc804\uc740 \ub3c4\uc804 \uacfc\uc81c \uc5c6\uc774 \uc774\ub904\uc9c0\ub294 \uac83\uc740 \uc544\ub2c8\ub2e4. \uba54\uc2a4\uaebc\uc6c0\uc774\ub098 \uc124\uc0ac\uc640 \uac19\uc740 \uc18c\ud654\uae30\uacc4 \ubd80\uc791\uc6a9\uc774 \uce58\ub8cc \uc21c\uc751\ub3c4\ub97c \uc81c\ud55c\ud560 \uc218 \uc788\ub2e4. \ub610\ud55c \uc774\ub7ec\ud55c \uc57d\uc81c\uc758 \ub192\uc740 \ube44\uc6a9\uc740 \uc811\uadfc\uc131\uc744 \uc800\ud574\ud558\uc5ec \uac74\uac15 \ubd88\ud3c9\ub4f1\uc744 \uc2ec\ud654\uc2dc\ud0a8\ub2e4. \ub9c8\uc9c0\ub9c9\uc73c\ub85c, \uce58\ub8cc\ub97c \uc911\ub2e8\ud558\uba74 \uccb4\uc911\uc774 \ub2e4\uc2dc \uc99d\uac00\ud558\ub294 \uacbd\uc6b0\uac00 \ub9ce\uc73c\uba70, \uc774\ub294 \uc7a5\uae30\uc801\uc778 \uc811\uadfc\uc758 \ud544\uc694\uc131\uc744 \uac15\uc870\ud55c\ub2e4.<\/p>\n

\ub530\ub77c\uc11c \ube44\ub9cc\uc740 \ub354 \uc774\uc0c1 \uc758\uc9c0\ub825\uc758 \ubb38\uc81c\ub85c \uc5ec\uaca8\uc9c0\uc9c0 \uc54a\uc73c\uba70, \uc0dd\ubb3c\ud559, \uc720\uc804\ud559, \uc0dd\ud65c \ubc29\uc2dd\uc774 \ubcf5\uc7a1\ud558\uac8c \uc5bd\ud78c \ub2e4\uc778\uc131 \uc9c8\ubcd1\uc73c\ub85c \uc778\uc2dd\ub418\uace0 \uc788\ub2e4. \ub819\ud2f4\uacfc GLP-1\uacfc \uac19\uc740 \ud638\ub974\ubaac\uc5d0 \ub300\ud55c \uc774\ud574\uc640 \uc720\uc804\uc801 \uc694\uc778\uc758 \uc2dd\ubcc4\uc5d0\uc11c \uc774\ub8e8\uc5b4\uc9c4 \ucd5c\uadfc\uc758 \uc9c4\uc804\uc740 \uc774 \uc9c8\ubcd1\uc744 \ub2e4\ub8e8\ub294 \ubc29\uc2dd\uc744 \ubcc0\ud654\uc2dc\ud0a4\uace0 \uc788\ub2e4. \ud604\uc7ac \uce58\ub8cc\ubc95\ub4e4\uc740 \uc720\ub9dd\ud558\uae34 \ud558\uc9c0\ub9cc, \ubaa8\ub4e0 \uc0ac\ub78c\ub4e4\uc774 \uc811\uadfc\ud560 \uc218 \uc788\uace0 \uc7a5\uae30\uc801\uc73c\ub85c \uc9c0\uc18d \uac00\ub2a5\ud574\uc9c0\uae30 \uc704\ud574 \uc544\uc9c1 \ub354 \ubc1c\uc804\ud574\uc57c \ud55c\ub2e4.<\/p>\n

\n

Sources du site<\/h2>\n

Source officielle de l\u2019\u00e9tude<\/h3>\n

DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1007\/s13353-026-01084-5<\/a><\/p>\n

Titre\u00a0:<\/strong> Unravelling obesity: from leptin to glucagon-like peptide-1 receptor agonists<\/p>\n

Revue : <\/strong> Journal of Applied Genetics<\/p>\n

\u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n

Auteurs : <\/strong> Taiwo Oluwafemi Idowu; Agata Chmurzynska<\/p>\n","protected":false},"excerpt":{"rendered":"

\ube44\ub9cc\uc774 \uc720\uc804\uc790\uc640 \ud638\ub974\ubaac \uc0ac\uc774\uc5d0\uc11c \ube44\ubc00\uc744 \ub4dc\ub7ec\ub0b4\ub2e4 \ube44\ub9cc\uc740 \ud604\uc7ac \uc804 \uc138\uacc4 \uc778\uad6c\uc758 \uc57d 30%\ub97c \ucc28\uc9c0\ud558\uba70, \uc774\ub294 1975\ub144 \uc774\ud6c4\ub85c 3\ubc30\ub098 \uc99d\uac00\ud55c \uc218\uce58\uc774\ub2e4. \uc624\ub7ab\ub3d9\uc548 \uc5d0\ub108\uc9c0 \uc12d\ucde8\uc640 \uc18c\ubaa8\uc758 \ub2e8\uc21c \ubd88\uade0\ud615\uc73c\ub85c \uc5ec\uaca8\uc84c\ub358 \uc774 \ubcf5\uc7a1\ud55c \uc9c8\ubcd1\uc740 \uc0ac\uc2e4 \uc720\uc804\uc790, \ud658\uacbd, \ud638\ub974\ubaac \uc2e0\ud638 \uac04\uc758 \ubc00\uc811\ud55c \uc0c1\ud638\uc791\uc6a9\uc758 \uacb0\uacfc\uc774\ub2e4. \uc774\ub97c \ub4b7\ubc1b\uce68\ud558\ub294 \uba54\ucee4\ub2c8\uc998\uc774 \uc810\ucc28 \ub354 \uc798 \uc774\ud574\ub418\uace0 \uc788\uc73c\uba70, \uc774\ub294 \ub354 \ud45c\uc801\ud654\ub418\uace0 \ud6a8\uacfc\uc801\uc778 \uce58\ub8cc\ubc95\uc73c\ub85c \uc774\uc5b4\uc9c0\uace0 \uc788\ub2e4. \uc774\ub7ec\ud55c… \ube44\ub9cc\uc774 \uc720\uc804\uc790\uc640 \ud638\ub974\ubaac \uc0ac\uc774\uc5d0\uc11c \ube44\ubc00\uc744 \ub4dc\ub7ec\ub0b4\ub2e4<\/span> \uacc4\uc18d \uc77d\uae30<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2,5,7],"tags":[],"class_list":["post-25","post","type-post","status-publish","format-standard","hentry","category-2","category-5","category-7","entry"],"_links":{"self":[{"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/posts\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":1,"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/posts\/25\/revisions"}],"predecessor-version":[{"id":26,"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/posts\/25\/revisions\/26"}],"wp:attachment":[{"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/media?parent=25"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/categories?post=25"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biologistjournal.com\/ko\/wp-json\/wp\/v2\/tags?post=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}