M\u1ed9t b\u01b0\u1edbc ti\u1ebfn l\u1edbn trong vi\u1ec7c hi\u1ec3u bi\u1ebft v\u1ec1 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 cho th\u1ea5y t\u00ecnh tr\u1ea1ng c\u1ee7a tuy\u1ebfn \u1ee9c \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng trong th\u00e0nh c\u00f4ng c\u1ee7a li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch. C\u01a1 quan n\u00e0y, th\u01b0\u1eddng b\u1ecb b\u1ecf qua \u1edf ng\u01b0\u1eddi tr\u01b0\u1edfng th\u00e0nh, r\u1ea5t c\u1ea7n thi\u1ebft cho s\u1ef1 tr\u01b0\u1edfng th\u00e0nh c\u1ee7a c\u00e1c t\u1ebf b\u00e0o lympho T, nh\u1eefng t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch nh\u1eafm m\u1ee5c ti\u00eau v\u00e0o c\u00e1c kh\u1ed1i u. M\u1ed9t nghi\u00ean c\u1ee9u g\u1ea7n \u0111\u00e2y ch\u1ec9 ra r\u1eb1ng nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 tuy\u1ebfn \u1ee9c kh\u1ecfe m\u1ea1nh h\u01a1n ph\u1ea3n \u1ee9ng t\u1ed1t h\u01a1n v\u1edbi li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch, b\u1ea5t k\u1ec3 lo\u1ea1i ung th\u01b0 n\u00e0o.<\/p>\n
C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u \u0111\u00e3 ph\u00e2n t\u00edch h\u01a1n 3.400 b\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c lo\u1ea1i ung th\u01b0 kh\u00e1c nhau, bao g\u1ed3m ph\u1ed5i, u h\u1eafc t\u1ed1 v\u00e0 th\u1eadn. Nh\u1edd ph\u01b0\u01a1ng ph\u00e1p tr\u00ed tu\u1ec7 nh\u00e2n t\u1ea1o \u00e1p d\u1ee5ng cho c\u00e1c x\u00e9t nghi\u1ec7m ch\u1ee5p c\u1eaft l\u1edbp ng\u1ef1c, h\u1ecd \u0111\u00e3 \u0111\u00e1nh gi\u00e1 s\u1ee9c kh\u1ecfe c\u1ee7a tuy\u1ebfn \u1ee9c. K\u1ebft qu\u1ea3 cho th\u1ea5y nh\u1eefng ng\u01b0\u1eddi c\u00f3 tuy\u1ebfn \u1ee9c ho\u1ea1t \u0111\u1ed9ng t\u00edch c\u1ef1c h\u01a1n c\u00f3 nguy c\u01a1 ti\u1ebfn tri\u1ec3n b\u1ec7nh th\u1ea5p h\u01a1n v\u00e0 th\u1eddi gian s\u1ed1ng k\u00e9o d\u00e0i h\u01a1n. M\u1ed1i quan h\u1ec7 n\u00e0y v\u1eabn t\u1ed3n t\u1ea1i ngay c\u1ea3 khi t\u00ednh \u0111\u1ebfn c\u00e1c d\u1ea5u \u1ea5n sinh h\u1ecdc kh\u00e1c nh\u01b0 g\u00e1nh n\u1eb7ng \u0111\u1ed9t bi\u1ebfn c\u1ee7a kh\u1ed1i u ho\u1eb7c bi\u1ec3u hi\u1ec7n c\u1ee7a protein PD-L1, th\u01b0\u1eddng \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 d\u1ef1 \u0111o\u00e1n ph\u1ea3n \u1ee9ng v\u1edbi \u0111i\u1ec1u tr\u1ecb.<\/p>\n
Thymus s\u1ea3n xu\u1ea5t c\u00e1c t\u1ebf b\u00e0o lympho T non, r\u1ea5t c\u1ea7n thi\u1ebft cho m\u1ed9t ph\u1ea3n \u1ee9ng mi\u1ec5n d\u1ecbch \u0111a d\u1ea1ng. \u1ede nh\u1eefng b\u1ec7nh nh\u00e2n c\u00f3 tuy\u1ebfn \u1ee9c kh\u1ecfe m\u1ea1nh, ng\u01b0\u1eddi ta quan s\u00e1t th\u1ea5y s\u1ef1 \u0111a d\u1ea1ng h\u01a1n c\u1ee7a c\u00e1c th\u1ee5 th\u1ec3 T trong m\u00e1u v\u00e0 c\u00e1c kh\u1ed1i u, d\u1ea5u hi\u1ec7u c\u1ee7a m\u1ed9t h\u1ec7 th\u1ed1ng mi\u1ec5n d\u1ecbch m\u1ea1nh m\u1ebd h\u01a1n. Ng\u01b0\u1ee3c l\u1ea1i, tuy\u1ebfn \u1ee9c suy y\u1ebfu, th\u01b0\u1eddng li\u00ean quan \u0111\u1ebfn tu\u1ed5i t\u00e1c ho\u1eb7c c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb tr\u01b0\u1edbc \u0111\u00f3, h\u1ea1n ch\u1ebf kh\u1ea3 n\u0103ng ph\u00f2ng th\u1ee7 n\u00e0y.<\/p>\n
Ph\u00e1t hi\u1ec7n n\u00e0y g\u1ee3i \u00fd r\u1eb1ng vi\u1ec7c \u0111\u00e1nh gi\u00e1 s\u1ee9c kh\u1ecfe c\u1ee7a tuy\u1ebfn \u1ee9c c\u00f3 th\u1ec3 tr\u1edf th\u00e0nh m\u1ed9t c\u00f4ng c\u1ee5 ti\u00eau chu\u1ea9n \u0111\u1ec3 c\u00e1 nh\u00e2n h\u00f3a c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb. N\u00f3 c\u0169ng m\u1edf ra con \u0111\u01b0\u1eddng cho c\u00e1c chi\u1ebfn l\u01b0\u1ee3c nh\u1eb1m t\u00e1i t\u1ea1o tuy\u1ebfn \u1ee9c, t\u1eeb \u0111\u00f3 c\u1ea3i thi\u1ec7n hi\u1ec7u qu\u1ea3 c\u1ee7a li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch. Kh\u00f4ng gi\u1ed1ng nh\u01b0 c\u00e1c d\u1ea5u \u1ea5n sinh h\u1ecdc hi\u1ec7n t\u1ea1i, t\u1eadp trung v\u00e0o kh\u1ed1i u, c\u00e1ch ti\u1ebfp c\u1eadn n\u00e0y xem x\u00e9t t\u00ecnh tr\u1ea1ng chung c\u1ee7a b\u1ec7nh nh\u00e2n, mang l\u1ea1i m\u1ed9t c\u00e1i nh\u00ecn to\u00e0n di\u1ec7n h\u01a1n trong cu\u1ed9c chi\u1ebfn ch\u1ed1ng ung th\u01b0.<\/p>\n
DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1038\/s41586-026-10243-x<\/a><\/p>\n Titre\u00a0:<\/strong> Thymic health and immunotherapy outcomes in patients with cancer<\/p>\n Revue : <\/strong> Nature<\/p>\n \u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n Auteurs : <\/strong> Simon Bernatz; Vasco Prudente; Suraj Pai; Asbj\u00f8rn K. Attermann; Alessandro Di Federico; Andrew Rowan; Selvaraju Veeriah; Lars Dyrskj\u00f8t; Leonard N\u00fcrnberg; Joao V. Alessi; Patrick A. Ott; Elad Sharon; Allan Hackshaw; Nicholas McGranahan; Christopher Abbosh; Raymond H. Mak; Danielle Bitterman; Mark Awad; Biagio Ricciuti; Charles Swanton; Mariam Jamal-Hanjani; Nicolai J. Birkbak; Hugo J. W. L. Aerts<\/p>\n","protected":false},"excerpt":{"rendered":" Thymus c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 c\u1ee7a li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch ch\u1ed1ng ung th\u01b0? M\u1ed9t b\u01b0\u1edbc ti\u1ebfn l\u1edbn trong vi\u1ec7c hi\u1ec3u bi\u1ebft v\u1ec1 c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 cho th\u1ea5y t\u00ecnh tr\u1ea1ng c\u1ee7a tuy\u1ebfn \u1ee9c \u0111\u00f3ng m\u1ed9t vai tr\u00f2 quan tr\u1ecdng trong th\u00e0nh c\u00f4ng c\u1ee7a li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch. C\u01a1 quan n\u00e0y,… Continue reading Thymus c\u00f3 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn hi\u1ec7u qu\u1ea3 c\u1ee7a li\u1ec7u ph\u00e1p mi\u1ec5n d\u1ecbch ch\u1ed1ng ung th\u01b0?<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[5,3,2],"tags":[],"class_list":["post-17","post","type-post","status-publish","format-standard","hentry","category-khoa-hoc-cong-nghe","category-nhan-dao-con-nguoi","category-suc-khoe","entry"],"_links":{"self":[{"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/posts\/17","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/comments?post=17"}],"version-history":[{"count":1,"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/posts\/17\/revisions"}],"predecessor-version":[{"id":18,"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/posts\/17\/revisions\/18"}],"wp:attachment":[{"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/media?parent=17"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/categories?post=17"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/biologistjournal.com\/vi\/wp-json\/wp\/v2\/tags?post=17"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}